LAUNCHXL-CC2650: CC2650 Custom Board Cannot Flash Hex File Using SmartRF Flash programmer

Part Number:LAUNCHXL-CC2650

Hello, i'm create CC2650 Custom Board, I try Example program Project Zero, at the first flash CC2650 is Succesfully, but the second Flash, CC2650 Not Detected and cannot Flash Again, what wrong about my Custom Board??